LONDON -The so-called "Big 4" men who have won 35 of 37 of the past Grand Slam singles titles?- Novak Djokovic, Rafael Nadal, Andy Murray and Roger Federer?- are all around for the second week at Wimbledon, joined by the new major winner on the block, Australian Open champion Stan Wawrinka.

The same can't be said on the women's side, where top-seeded and five-time champion Serena Williams won't see any action at the All-England Club in Week 2 except in doubles with her sister Venus, another five-time Wimbledon winner who is also out of singles.

With Serena out and second-seeded Li Na also a third-round loser, it marks the first time in the Open era that the top two women's seeds haven't advanced to Wimbledon's fourth round.