George Clooney has "chemistry" with all his female co-stars.

The Hollywood hunk - who appears alongside Anna Kendrick and Vera Farmiga in 'Up In The Air' - has an automatic connection with all of his screen lovers, who can't help but be attracted to him.

"He's a goofball. He's a clown. It's just so good to be in his presence, and as a scene partner, anything goes. It's a real circus with him on set. It's carefree and loving and warm."

Vera's colleague Anna - who portrays businesswoman Natalie - has also spoken out about George's flirtatious ways, admitting she was initially "terrified" of him but he soon put her at ease.

She told Empire magazine: "During the camera test he was making fun of my hair. If it was anybody else that you'd just met, you'd be like, 'What's this guy's problem?' But it's George Clooney. Obviously, he is really intimidating as a sort of iconic figure. Really terrifying.

"Then the second that you meet him properly, you know you're going to feel that he's a normal guy in a matter of days. He is one of the most famous people on the planet, but he has a real talent for making you feel like you've known him forever."